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Test takers must rely on their knowledge gained from the experiences of their intern year, supplemented by a concise, yet high-yield, review of testable information. Because of the emphasis on patient management in the examination, this book has been designed to provide a realistic clinical scenario for the many tested diagnoses. The organization of this book is unlike other reviews for the USMLE Step 3 in that nearly all of the information is presented in a case-based format.

Each case consists of an extensive history and physical for a presenting patient, multiple diagnostic studies performed during the work-up, the diagnosis made due to this work-up, the treatment administered, and the follow-up of the patient following therapy.

Following each case, each of the most likely conditions in the differential diagnosis is reviewed, and the reason why each diagnosis is correct or incorrect is explained. This type of review is a better reproduction of the thought processes of the new resident physician than a simple iteration of facts.

It seeks to reproduce the clinical decisions that a resident physician is required to make on a daily basis. In addition, the limited amount of time available for test preparation has been considered during the writing of this book. The reviews of each diagnosis are concise and designed to include only the high-yield information that is vital on test day. It is not intended to be a self-assessment of testable information, but rather a presentation of how certain conditions may present and how they are appropriately managed.

Please feel free to forward any comments to me at Step-Up lww. I wish you all the best of luck in taking and passing this final stage of the USMLE examination series.

Although the demands of residency are significant, the completion of this test is yet another hurdle that you will have cleared on the road to completing medical education and beginning a complete practice of medicine.

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